To flee or depart quickly.
Don't run off before the end of the event.
To make photocopies, or print.
Please run off a couple dozen more flyers to pass out.
To write something quickly.
Shakespeare could run off a play in just a couple of days.
(of a liquid) To pour or spill off or over.
They kept a barrel to store rainwater that has run off the roof.
To cause to flow away.
to run off a charge of molten metal from a furnace
To chase someone away.
If anyone comes into this field, the bull will soon run them off.
To operate by a particular energy or fuel source.
This radio runs off batteries.